Exposure, intake and dose models

This folder provides information on, and access to, methods and tools for modelling human exposure, intake or doses of environmental contaminants, as part of integrated environmental health impact assessments. 

Item Type Description
IndusChemFate Factsheet Generic physiologically based pharmacokinetic model to estimate blood and urine concentrations of multiple chemicals; developed to predict exposure in workers and consumers, and considers inhalation, dermal and oral exposures.  Available free.
PBPK model for cadmium Factsheet Model based on  Kjellström and Nordberg (1978) for predicting invididual and population based exposure to cadmium from oral and inhalatory intake
PBTK model for dioxin Factsheet Physiologically based toxicokinetics modelling process to simulate ingestion exposures to 2,3,7,8-tétra-chloro-p-dioxin (TCDD) for a woman over her whole life; the model computes various measures of internal dose as a function of time