Exposure-response functions: protocol and guidelines
The attached document was compiled as part of the EU-funded INTARESE project, which contributed ot the development of this Toolbox.
It sets out a general methodology for estimating exposure-response functions (ERFS), in the context of intergrated environmental health impact assessment. It defines principles for selecting exposure-response relationships for quantification, reviews methods for deriving exposure-response functions (including techniques of systematic review and expert elicitation), outlines methods for characterising uncertainties in ERFs, and discusses approaches for combining epidemiologically- and toxicolologically-based information where needed.
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